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Christina Applegate Details “Screaming” in Pain Amid MS Battle

Christina Applegate Details “Screaming” in Pain Amid MS Battle
Christina Applegate Details “Screaming” in Pain Amid MS Battle


Christina Applegate is getting candid about her health journey.

The Dead to Me star recently detailed just how agonizing the effects of her multiple sclerosis (MS) can be.

“Everybody has different ways of it showing up,” Christina, 52, said on the Nov. 5 episode of her MeSsy podcast, co-hosted by The Sopranos alum Jamie-Lynn Sigler, who also lives with MS. “I lay in bed screaming. Like, the sharp pains, the ache, the squeezing.”

In addition to the severity of her pain, the Married with Children alum—who received her diagnosis in 2021—also shared she now experiences symptoms in places she hadn’t previously.

“I can’t even pick up my phone sometimes,” she went on, “because now it’s traveled into my hands. So I’ll try to go get my phone or get my remote to turn on the TV or whatever, and sometimes I can’t even hold them.”

MS is defined as an auto-immune disease which affects communication between the brain and the rest of the body, according to the Mayo Clinic. And while Christina continues to fight the mysterious disease, she did reveal one of her most effective—and perhaps unlikely—coping mechanisms.

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